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Home » Science » Biology » Immunology Antibodies
Sites about the defense mechanism of the body which are dependent on the humoral aspects of immunity as compared to the cell-mediated aspects which secrete Cytokines.Sites may include the mechanisms of interaction of antibody with antigen, as well as the cascade sequence that this invokes, through the complement system.
Sites may describe the molecular structure of antibodies, their classification and problems associated with their synthesis, such as the glycosylation of recombinant proteins, to mimic mammalian species, but are produced in plant cell host, "Plantibodies".
Sub-Categories:
| Humanization bY Design - Resources describing the process of creating humanized antibodies, their uses and their history. Maintained by Birkbeck College, London, UK.
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| | Muscle Autoantibodies - Antibodies and complement in myopathies and neuromuscular junction disorders. Maintained by Washington University School of Medicine, St. Louis, Missouri.
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| | Antibodies - Structure and Sequence - Attempts to summarize useful information on antibody structure and sequence. Provides a query interface to the Kabat antibody sequence data, general information on antibodies and crystal structures, and links.
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| | The Antibody Resource Page - Resource guide to antibody research and suppliers.
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| | Mike's Immunoglobulin Structure and Function - Molecular images, history of monoclonal antibodies, activity related to sequence, and humanisation for therapy. Includes information on the maintainer and his research group at Cambridge, UK.
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| | Antibody Questions - Interface to introduce the various immunoassays in current use, production and purification methods, labeling and assay development, from a manufacturer, with worldwide distribution in Pierce Biotechnology, Inc., Rockford, IL.
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| | MSRS Catalog of Primary Antibodies - Database of immunoglobulins, monoclonals and whole sera, to nucleic acids and markers, with host and antigen species, clone and isotype id, and distribution details. Includes online demo with CD available for purchase from Key West, Florida.
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| | Antibodies and Therapy - Article on the history of vaccination, the role of the humoral response in organ and bone marrow transplantation, leukaemia and lymphoma, and rheumatoid disease. Includes links to laboratories at the Therapeutic Antibody Centre, Oxford, UK.
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| | Conjugation of monoclonal antibodies - Straightforward procedures for conjugation of proteins (mainly antibodies) to fluorescent dyes.
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| | HLA Matching, Antibodies, and You - Tissue matching and antibody production, for patients undergoing a transplant.
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| | The Mouse in Science: Monoclonal Antibodies - Brief overview, ELISA information, and ethics.
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| | Monoclonal Antibodies - Introduction, uses (including in human medicine), problems and what may happen in the future.
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| | Alzforum: Antibody Directory - Tables describing antibodies used in laboratories and from manufacturers, organised by antigen.
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| | Pluckthun, Andreas - Laboratory concentrating on protein engineering and directed molecular evolution, especially of immunoglobulins. Includes PDFs of molecular structures, publications since 1985, and contacts at the University of Zurich in Switzerland.
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| | Endotoxin-Core Antibodies - An explanation of the use of this assay in studies of endotoxemia in Edinburgh, Scotland.
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